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How does cryotherapy:
The cold causes cell necrosis through sequence of mechanisms that can be summarized:
1) formation of intracellular ice crystals that cause the mechanical cell lysis
2) abnormal cellular concentration of electrolytes leading to irreversible changes in the pH of the skin
3) formation of ice crystals in extracellular spaces , increasing the osmotic gradient and a call from the cell of water that ends up collapsed:
4) thermal shock with altered lipoprotein phones. The local circulatory changes
complete necrosis district. In fact, when the local temperature drops to -50 ° C are carried out phenomena of stasis, venous thrombosis and capillary tissue. The amount of
crionecrosi, and that of the vascular changes depend on many factors such as:
1) freezing time
2) time to thaw
3) amplitude of the halo of frost perilesional
4) duration of exposure of cells at temperatures well below freezing:
5) minimum temperatures reached in the target tissue.
has been shown that rapid freezing promotes the formation of intracellular ice, while a slow freezing promotes that of the extracellular ice.
The dermatologist then thanks to the 'action of liquid nitrogen will burn your imperfections that will soon become necrotic, forming a crust, which soon fall. It better not take the sun on the exposed side for at least a month.